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New Biomarker Allows Better Prediction of Survival for Patients with Colorectal Metastases

Liver metastases are formed from cancer cells that have originated in other organs and migrated to the liver via the bloodstream. Colorectal cancer (cancer of the colon/rectum) can be successfully treated by surgical resection of the metastases in combination with chemotherapy. In collaboration with the University of Southern California (USA), a MedUni Vienna research team has now identified a new biomarker that allows better prediction of survival following surgical removal of the metastases, as well as a change in the clinical significance of the biomarker following chemotherapy.

Biomarkers Could Give Early Warning of Late Heart Transplant Rejection

Researchers at Boston Children’s Hospital have found a combination of biomarkers related to blood vessel and tissue injury that, when measured together, could signal when a transplanted heart is becoming damaged to the point of failure, a process that is often undetected. The markers would give doctors an opportunity to intervene and save a recipient’s heart, and also provide a starting point for identifying long-term rejection biomarkers for several kinds of organ transplants.