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Researchers Develop Urine Test for Heart Disease

Scientists at the University of Glasgow have developed a simple test to detect coronary artery disease by analysing urine samples.

The test looks for particular protein expressions, or biomarkers, associated with the disease and has been shown to have an accuracy rate of almost 90 per cent.

Edimer Pharmaceuticals Presents Study Results on Non-Invasive Sweat Gland Analysis as a Biomarker in XLHED Patients

Edimer Pharmaceuticals, a biotechnology company focused on developing an innovative therapy for the rare genetic disorder, X-linked Hypohidrotic Ectodermal Dysplasia (XLHED), today announced key findings of a study exploring novel approaches to the assessment of sweat function in males with XLHED. Affected individuals lack a normal sweat response, placing them at life-long risk for clinically-significant hyperthermia. The study reported on the use of non-invasive technologies for quantitative sweat function, and correlated these results with the nature and location of ectodysplasin A (EDA) gene defects associated with XLHED. Data analysis confirmed a consistent, quantifiable defect in sweat gland function as a disease biomarker in XLHED patients, even in the setting of normal sweat pore counts. The study outcomes were reported at the 60th Annual Meeting of the American Society of Human Genetics (ASHG) in Washington, D.C.

Caprion Proteomics Identifies Promising New Candidate Biomarkers to Predict Response to Hepatitis C Treatment

Caprion Proteomics announced today that it has identified promising candidate protein biomarker panels that appear to predict patient responsiveness to treatment for hepatitis C.

The study employed Caprion’s proprietary CellCarta mass spectrometry-based proteomics discovery platform to measure and compare the expression levels of thousands of proteins contained in blood samples collected from patients infected with the hepatitis C virus (HCV), in order to discover predictive biomarkers of sustained response to hepatitis C therapy.

Novel Biomarker May Predict Response to New VEGF Receptor Inhibitor

Researchers believe there may be a way to predict, based on individual tumors, those patients that are more likely to respond to the investigational new drug tivozanib.

Michael J. Fox Foundation Launches Parkinson’s Progression Markers Initiative (PPMI)

The Michael J. Fox Foundation has launched the Parkinson’s Progression Markers Initiative (PPMI) (www.michaeljfox.org/PPMI), the first-ever large-scale clinical study exclusively focused on identifying and validating Parkinson’s disease biomarkers.