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Alzheimer’s Consortium Identifies Five New Genes for Disease Risk

The Alzheimer’s Disease Genetics Consortium (ADGC) led by the University of Pennsylvania School of Medicine, the University of Miami, and the Boston University School of Medicine, recently identified five new genes linked to late-onset Alzheimer’s disease. The study, published in the journal Nature Genetics, describes data on ABCA7, MS4A6A/MS4A4E, CD2AP, CD33 and EPHA1, each of which contribute to the risk of dementia later in life.

First Blood Test to Determine Cognitive Impairment in Parkinson’s Disease Developed by Penn Researchers

Researchers at the University of Pennsylvania School of Medicine’s Udall Center for Parkinson’s Research have developed the first blood-based biomarker test to predict cognitive decline in Parkinson’s disease (PD). If results can be replicated and standardized in other Parkinson patients, by other investigators, the test could be a useful tool to use in selecting patients for the development of new drugs that can slow or prevent this complication of the disease.

Penn Researchers Receive $12 Million NIH Grant to Develop Personalized Approach to Smoking Cessation

A variety of smoking cessation treatments are currently available for the more than 18 million adult Americans try to quit smoking each year, but success rates vary widely. Despite the importance of quitting smoking, more personalized approaches to smoking cessation treatment are needed to help smokers pick the right method that will work best for them. A major new personalized medicine clinical trial, led by addiction researchers at the University of Pennsylvania, will study how a smokers’ genetic make-up influences their quitting success.