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Proteins in Mother’s Blood Can Predict Risk for Serious Pregnancy Complications in Women with Lupus

Researchers at Hospital for Special Surgery (HSS) have released a second set of results from the PROMISSE study showing that angiogenic biomarkers measured in maternal blood successfully predict whether or not a woman with lupus is likely to experience serious complications during pregnancy – complications that could negatively affect her health or that of her baby.

Exagen Diagnostics Launches Prognostic Panel

Exagen Diagnostics, Inc., a leading medical diagnostic company focused in rheumatology, recently announced the addition of the Avise SLE Prognostic panel to its testing services.

Berg and Medical University of South Carolina Announce First of Its Kind Collaboration to Discover Lupus Biomarker

Berg and the Medical University of South Carolina recently announced a strategic partnership, designed to identify new therapeutic pathways and potential biomarkers to treat Lupus, the autoimmune disease affecting one in every 2,000 people and one in every 250 young African American women.

Sanguine BioSciences Signs Agreements with More than 200 Partners to Enable Efficient Personalized Medicine Research

Sanguine BioSciences, a biotechnology company enabling personalized medicine research, today announced that it has signed commercial agreements with, and received orders from, more than 200 biomedical researchers at academic, biotechnology and pharmaceutical companies, to enable more efficient personalized medicine research. Ongoing agreements are in place with a wide range of organizations, ranging from startups, such as Inhibrx, to contract research organizations, such as Applied Immunology, and major drug developers, such as Vertex Pharmaceuticals.

Sanguine directly engages patients diagnosed with severe and chronic diseases to collect and de-identify biospecimen, medical history and other data that can be used in biomarker research. Traditional methods are to obtain biospecimen through hospitals, but this process can result in months of delays as the focus for physicians and staff is on diagnosis and treatment, not facilitating research efforts. By engaging patients directly, Sanguine can meet the needs of researchers and offer timely turnaround of biospecimen and medical data with diverse ranges for age, race, disease state, gender and treatments underway. The patient engagement tactics used by the company have led to a 95 percent retention rate, which also allow for follow-up draws for longitudinal studies.

“In a very short amount of time, and with only recently hiring our first few sales executives, our company has established agreements with ten of the largest drug developers in the world and continues to see high demand for our offering,” said Brian Neman, founder and chief executive officer of Sanguine. “Researchers have specific needs to complete studies in early discovery work, sometimes run with blood samples drawn the same day and other times requiring follow-up draws on exact time schedules, but traditional strategies to obtain these add months to the timeline. Our commitment to patient engagement, transparency and advocacy removes much of this wait time – accelerating the research and increasing the efficiency of the process overall.”

Sanguine is able to meet, review disclosures and collect blood samples in a patient’s home with its own phlebotomists in multiple major U.S. cities. Patients are also able to track how their de-identified biospecimen and data are used through the donor web portal. The company is able to collect and process blood from patients with any disease and has already built large libraries in multiple chronic and severe conditions, including Huntington’s disease, rheumatoid arthritis, systemic lupus erythematosus, Crohn’s disease, ulcerative colitis and others.

In order to maintain appropriate confidentiality, all samples are de-identified immediately upon collection. Sanguine maintains and reviews internal ethical guidelines for the procedures under high scrutiny from an independent review board.

Source: PR Newswire

Sanguine BioSciences Announces Distribution Partnership with AMS Biotechnology

Sanguine BioSciences, a biotechnology company enabling personalized medicine research, today announced a distribution partnership with AMS Biotechnology (AMSBIO) to make its products and services available to researchers in Europe.

Sanguine collects and de-identifies biospecimen, medical history and other data from patients diagnosed with severe and chronic diseases for use in biomarker research. Researchers traditionally obtain biospecimen through hospitals, but this process often proves inefficient as the focus for physicians and staff is on diagnosis and treatment, not facilitating research efforts. By connecting directly with patients, Sanguine can meet the needs of researchers and offer timely turnaround of biospecimen and medical data with diverse ranges for age, race, disease state, gender and treatments underway. The patient engagement tactics used by the company have led to a 95 percent retention rate, which also allow for follow-up draws for longitudinal studies.

“There is no denying that personalized medicine has become a significant area of interest for drug discovery, but there exists a gap between researchers who require biospecimen respective medical data, and patients who want to be a part of research efforts,” said Brian Neman, founder and chief executive officer of Sanguine. “We have engaged hundreds of patient subjects, and built a library of specimen and data that can effectively bridge this gap. We look forward to partnering with AMSBIO to make this service accessible to researchers around the world working in different therapeutic areas.”

Added Phillip Pridham-Field of AMSBIO, “Sanguine’s patient retention efforts allow researchers to collect the data they need with better turnaround time and with the potential for longitudinal studies. We believe they will be an excellent addition to our current product offerings for researchers in life sciences.”

Sanguine is able to meet, review disclosures and collect blood samples in a patient’s home with its own phlebotomists in multiple major U.S. cities. Patients are also able to track how their de-identified biospecimen and data are used through the donor web-portal. The company is able to collect and process blood from patients with any disease and has already built large libraries in multiple chronic and severe conditions, including Huntington’s disease, rheumatoid arthritis, systemic lupus erythematosus, Crohn’s disease, ulcerative colitis and others.
In order to maintain appropriate confidentiality, all samples are de-identified immediately upon collection. Sanguine maintains and reviews internal ethical guidelines for the procedures under high scrutiny from an independent review board.

Source: PR Newswire