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The Spinal Muscular Atrophy Foundation Announces a Biomarker Panel to Guide SMA Therapeutic Development

The Spinal Muscular Atrophy (SMA) Foundation announced today the launch of a biomarker assay panel for SMA using Myriad RBM’s Multi-Analyte Profiling (MAP) technology platform. The SMA-MAP panel is designed to evaluate the severity of SMA and disease progression and can be used to assess drug efficacy and shorten the duration of clinical trials for SMA therapeutics.

NextGen’s New Diagnostics Company Established

NextGen Group Plc (AIM: NGG), an AIM listed company providing biomarker discovery and testing services has completed the establishment of its new diagnostics subsidiary company (NextGen Sciences Dx Inc.). The board of NextGen believes that the creation of the diagnostics business as a separate corporate entity is an important milestone in the transformation of the Group from solely providing outsourced research work to owning a portfolio of valuable intellectual property.

SciClips Launches Cancer Biomarker Database

The success of personalized cancer therapeutics relies on the development of companion diagnostic assays that can identify the most appropriate cancer patient, tumor type and disease state. To address this need, SciClips, a Wisconsin-based open innovation platform company that enables scientists and researchers to collaborate and share research and ideas, recently launched a cancer (oncology) biomarker database.

PrognosDx Health and Accium BioSciences Enter Into Collaborative and Research Agreement to Develop Clinical Tests Based on Histone Biomarkers

PrognosDx Health, a pioneering company in cancer epigenetics, announced today that Dr. Jeffrey L. Wolf has joined its scientific advisory board. An expert in multiple myeloma and other hematopoietic malignancies, Dr. Wolf also specializes in bone marrow transplantation for treatment of a variety of cancers. Dr. Wolf is the Director of the Multiple Myeloma Program in the Division of Hematology and Oncology at the Helen Diller Family Comprehensive Cancer Center and a Clinical Professor of Medicine at UCSF.

It was also announced that PrognosDx Health and Accium BioSciences (Seattle, Washington) have entered into a collaboration agreement aimed at co-developing and commercializing a series of high-value predictive histone biomarker tests. The collaboration combines the expertise and breakthrough epigenetic platform technology of PrognosDx with the accelerator mass spectrometry (AMS) platform of Accium BioSciences.

Drug Safety, Efficacy, and Potential New Cancer Biomarker Predicted by NextBio

New research presented this week highlights the ability of NextBio to help life scientists and clinicians investigate publicly available genomic data to assess biological mechanisms underlying drug toxicity, as well as discover prospective cancer biomarkers for further validation. The unique capabilities of NextBio to search and make discoveries, not possible by other methods, from the massive amounts of genomic data increasingly available in the public domain is the subject of two poster presentations at the American Society of Human Genetics/International Congress of Human Genetics meeting in Montreal, October 11-15.