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NIH to Fund Research on Alcohol-related Biomarkers

The National Institute on Alcohol Abuse and Alcoholism aims to fund small businesses and support the technology transfer of new biomarkers that can be used to detect alcohol-related organ damage and fetal exposure to alcohol, according to a new NIAAA grant notice.

Spinal-Fluid Test Is Found to Predict Alzheimer’s

Researchers report that a spinal fluid test can be 100 percent accurate in identifying patients with significant memory loss who are on their way to developing Alzheimer’s disease.

Although there has been increasing evidence of the value of this and other tests in finding signs of Alzheimer’s, the study, which will appear Tuesday in the Archives of Neurology, shows how accurate they can be. The new result is one of a number of remarkable recent findings about Alzheimer’s.

After decades when nothing much seemed to be happening, when this progressive brain disease seemed untreatable and when its diagnosis could be confirmed only at autopsy, the field has suddenly woken up.

New UC Davis Study Finds Early Alzheimer’s Identification Method

Abnormal brain images combined with examination of the composition of the fluid that surrounds the spine may offer the earliest signs identifying healthy older adults at risk of developing Alzheimer’s disease, well before cognitive problems emerge, a study by researchers at UC Davis has found.

ART-funded Researchers Find Biomarker Associated with Alzheimer’s

Research led by the Institute of Psychiatry (IoP) King’s College London (KCL) and part-funded by the Alzheimer’s Research Trust has found that certain protein levels in blood could be an early marker of Alzheimer’s.

The international team of scientists also found that higher levels of the protein, called clusterin, were related to more severe and rapid memory loss and greater brain shrinkage. Their findings could lead to development of a blood test to help identify who would benefit from early treatment for Alzheimer’s and also whether treatments were working to delay or prevent brain damage.

Multiple biomarker index useful only in asymptomatic patients with mild atherosclerosis

A multiple biomarker index, one that includes markers of inflammation, is only modestly associated with increased risks of coronary heart disease and cardiovascular disease in asymptomatic patients, according to the results of a new study [1]. The increased risk of events for patients with a biomarker score above the median occurs mainly in those with a mild amount of existing atherosclerosis, according to investigators.