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Somalogic Researchers Describe Revolutionary New Approach to Protein Analysis and Application to Early Diagnosis of Lung Cancer

Even with astounding advances in genomic science, genetic analysis of disease remains largely a measure of risk rather than actual disease state. A truer and more immediate measure of health can be obtained by analysis of proteins, especially those that are “biomarkers” of disease state. Until now, proteomic technologies have lacked the sensitivity, scale, and robustness to untangle the vast differences in protein types and concentration levels that underlie complex human biology and disease. In two papers published on December 2 in the open-access scientific journal PLoS One, researchers at SomaLogic, Inc., and their collaborators describe a revolutionary new approach to biomarker detection and demonstrate its potential diagnostic power in a large-scale study that identifies a panel of biomarkers that can detect lung cancer in its early – and treatable – stages.

Detecting Cancer with the Prick of a Finger

Researchers at BYU have created a micro device that could both decrease the amount of blood and time needed to test for cancer-markers in a patient’s blood.

Chemistry professor Adam Woolley’s research, published in a recent issue of the journal, Lab on a Chip, details the device and technique that would allow for effective detection of biomarkers in a blood sample in a matter of minutes rather than days or weeks.

NPL Scientists Improve Biomarker Detection Technique

Scientists from NPL’s Biotechnology group have developed a new strategy to enable quicker and more precise detection of biomarkers – proteins which indicate disease. The work marks a new research direction for the group, and they hope the technique is an early step towards tools to detect Alzheimer’s and cancer at the molecular level.