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TcLand Teams Up with Spanish Institute to Develop Assay for Predicting Response To TNFalpha Therapy

TcLand Expression is teaming up with the Hospital Vall d-Hebron Research Institute (HVIR) in Spain to develop a biomarker-based assay for predicting individual patients’ responses to TNFα blocker therapy for rheumatoid arthritis (RA). The collaboration agreement gives TcLand exclusive, worldwide rights to HVIR’s IP covering response-related biomarkers discovered by the Institute’s Sara Marsal, M.D., director of the Grup de Recerca de Reumatologia.

Phadia Chooses Aushon BioSystems’ Microarray Technology to Accelerate Diagnostic Allergen and Autoimmunity Assay Development

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, announced today that Phadia, the world leader in allergy blood testing diagnostics, will utilize the Aushon 2470 Arrayer technology in its Multiplexing Diagnostics GmbH division. The 2470 will enable Phadia to advance its research efforts focusing on the characterization of new allergens, and the discovery of patterns in molecular diagnosis for allergy and autoimmunity.

Clarient Receives Patents for Taxane Biomarker

Clarient, Inc., a premier technology and services resource for pathologists, oncologists and the pharmaceutical industry, today announced that the United Kingdom Patent Office has granted a U.K. patent on the Company’s TLE3 biomarker, a marker which may be used to predict which cancer patients will respond favorably to taxane therapy. In addition, the Company has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for a U.S. patent on the TLE3 biomarker. Other patents for the TLE3 biomarker are pending in the U.S., Canada, Japan, China, India and elsewhere in Europe.

Quintiles Announces Suite of PI3K Biomarker Assays to Advance Oncology Therapies Targeting this Cancer Pathway

Quintiles today announced a comprehensive suite of biomarker assays to help bio pharmaceutical companies investigate the phosphoinositide 3-kinases (PI3K) cancer survival pathway, the focus of numerous anti-cancer therapies under development. Understanding the PI3K pathway is essential in developing new medicines to inhibit or block this pathway, thereby cutting off a metabolic function needed for certain cancers to survive.