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SomaLogic Publishes Proteomic Biomarker Analysis of Lung Cancer Tissue Samples

In a scientific paper published recently in the journal PLoS ONE, researchers from SomaLogic and the University of Washington in Seattle describe the first application of the SOMAscan proteomic assay technology to tissue samples. Working with both tumor and non-cancerous lung samples from patients with non-small cell lung cancer (NSCLC), they identified significant expression changes in 36 proteins, including 13 proteins not previously associated with the disease. These findings reveal significant new information about the biology underlying NSCLC, and have implications for improving early diagnosis and treatment.

Cancer Biomarker Study Data Presented at the 2011 AACR Meeting

A roundup of five research studies on cancer biomarkers that were presented earlier this week at the American Association for Cancer Research (AACR) 102nd Annual Meeting in Orlando, Florida.

Somalogic Researchers Describe Revolutionary New Approach to Protein Analysis and Application to Early Diagnosis of Lung Cancer

Even with astounding advances in genomic science, genetic analysis of disease remains largely a measure of risk rather than actual disease state. A truer and more immediate measure of health can be obtained by analysis of proteins, especially those that are “biomarkers” of disease state. Until now, proteomic technologies have lacked the sensitivity, scale, and robustness to untangle the vast differences in protein types and concentration levels that underlie complex human biology and disease. In two papers published on December 2 in the open-access scientific journal PLoS One, researchers at SomaLogic, Inc., and their collaborators describe a revolutionary new approach to biomarker detection and demonstrate its potential diagnostic power in a large-scale study that identifies a panel of biomarkers that can detect lung cancer in its early – and treatable – stages.