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Personalized Medicine on the Horizon for BC Cancer Patients

Genome British Columbia and the BC Cancer Foundation have joined forces to announce a major step forward in applying the power of genomics to personalized medicine. The innovative partnership stems from the strong focus of both organizations on the potential of genomics to improve patient outcomes in BC.

Detection of Key Epigenetic Biomarkers

Epigenetics refers to the study of heritable changes in genome function that occur without a change in the primary DNA sequence of an organism. One such change is DNA methylation, most frequently characterized by an enzymatic modification at the fifth position of cytosine (5-mC), present abundantly in the context of CpG dinucleotides. The formation and maintenance of 5-mC is catalyzed by cellular DNA (cytosine-5) methyltransferases (DNMTs).