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TTP Labtech and Almac Group’s Strategic Alliance Consolidates Fluorescence Lifetime Technology to Form a One-stop Shop for Compound Screening

A strategic alliance has been formed for the marketing and sale of a complete fluorescence lifetime (FLT) technology comprising Almac Group’s proprietary FLEXYTE® FLT reagents and assays, and TTP Labtech’s new ameon® microplate reader. Customers can now gain full access to support, and buy equipment and essential reagents all from TTP Labtech, underpinned, behind the scenes, by Almac’s manufacturing and new assay development expertise.

Almac Validates Novel Test for Ovarian Cancer Patients

Almac Group Ltd.’s Diagnostics Business Unit recently announced the validated results of the ALM AADx assay, a gene expression test that identifies a subgroup of high grade serous ovarian cancer (HGSOC) patients that have a good prognosis following standard of care chemotherapy.

Genomic Health and Almac Group Enter Exclusive In-Licensing Agreement to Develop and Commercialize Anthracycline Chemotherapy Benefit Test for High Risk Breast Cancer

Genomic Health, Inc. (Nasdaq: GHDX) and ALMAC GROUP Ltd recently announced that Genomic Health will exclusively license Almac Group’s technology and intellectual property to further develop, validate and subsequently commercialize a multi-gene test to predict benefit from DNA damage-based chemotherapy drugs, such as the commonly used anthracycline-based regimens, in breast cancer.  Such a test would be particularly useful for high-risk breast cancer patients who are eligible for chemotherapy based on their Oncotype DX® score.

Almac Offering TruSight Tumor Profiling Next-Generation Sequencing Service

Almac recently announced they are now offering a Tumor Profiling service running Illumina’s next-generation sequencing (NGS) TruSight Tumor™ panel as part of their biomarker discovery, development and delivery solutions.

Almac, a personalised medicine company with CAP accredited and CLIA certified laboratories, extends their portfolio of services by offering TruSight Tumor™ to complement its current range of RNA, DNA and protein based technologies for biomarker analysis.

Almac is currently running many bespoke diagnostic assays for pharma customers for early phase clinical trial enrichment. The TruSight Tumor™ panel enables additional profiling of these patient samples to provide Almac’s pharma partners with further important information on emerging biomarkers that may also impact drug response.
The TruSight Tumor™ panel was developed by Illumina for their MiSeq® system, allowing targeted DNA sequencing and reporting on the mutation status of 26 genes which are most commonly mutated in solid tumors including lung, colon, ovarian, melanoma and gastric cancers.

One of Almac’s key strengths is many years of experience in working with formalin fixed paraffin embedded (FFPE) tissue. The TruSight Tumor™ panel is specifically designed for use with FFPE samples, and enables the highest levels of sensitivity for mutation detection with limited DNA input requirements.

“Almac is committed to the development of personalised medicine through the delivery of a wide range of innovative solutions. We are pleased to announce the expansion of our NGS service to include TruSight Tumor™” said Professor Paul Harkin, President and Managing Director of Almac’s Diagnostic business unit.

Source: Almac

Almac Announces Launch of Next Generation Sequencing Service for Personalised Medicine

Almac today announced that it is launching a Next Generation Sequencing service to further expand its range of solutions supporting the development of personalised medicine. The purpose of this service is to support Almac’s BioPharma partners in the development of molecular tests for trial enrichment and companion diagnostic development, specifically focussing on targeted re-sequencing