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Biomarker Brief: August 26, 2011

Reading time: 2 – 3 minutes

Biomarker Brief is an occasionally recurring series highlighting particularly interesting articles on biomarkers and/or personalized medicine.

  • Biomarkers Wanted
    Many studies looking for proteomics-based biomarkers suffer from various forms of bias in terms of sample collection, analytical assays, and data manipulation and interpretation.
    [Chemical & Engineering News]
  • Einstein Researchers Demonstrate Need for More Careful Evaluation of Biomarker Reference Ranges
    Following up on the observation that clinicians were were seeing an unusual number of older white female patients diagnosed with high thyroid-stimulating hormone (TSH) levels and receiving thyroid hormone replacement therapy, Einstein researchers have discovered that the TSH reference range increases with age.
    [Albert Einstein College of Medicine]
  • Lack Of Diagnostics Slows Personalized Medicine
    According to the Tufts Center for the Study of Drug Development, many third-party payers are skeptical about the usefulness of certain companion diagnostics and are either denying or restricting test reimbursement.
    [Pharmalot]
  • Turning Blood into Gold: The Wellness Chip
    SomaLogic aims to be “a longitudinal biomarker monitoring company” with the vision of bringing together a variety of diagnostic assays into one simple blood test using proprietary reagents called SOMAmers.
    [Bio-IT World]
  • Tools for Affordable Health Care
    Rice University has pioneered the development of programmable microchip sensors that can serve as universal clinical tools and revolutionize the diagnostics industry. The bio-nano-chip (PBNC) system has the potential to replace hundreds of thousands of dollars’ worth of laboratory equipment while getting test results to patients in minutes instead of days.
    [Texas CEO Magazine]
  • Seeing Biomarkers with the Naked Eye
    A new ultra-sensitive and label-free technique to detect molecules has been developed by researchers at Boston University. The technique is based on a resonant scattering phenomena in plasmonic nanohole devices and allows cancer biomarkers to be seen with the naked eye.
    [nanotechweb.org]