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Archives for April 2016

The Michael J. Fox Foundation for Parkinson’s Research Announces Study to Measure Parkinson’s Protein throughout Body

The Michael J. Fox Foundation for Parkinson’s Research (MJFF) has launched the observational Systemic Synuclein Sampling Study (S4) to investigate the protein alpha-synuclein as a biomarker of Parkinson’s disease (PD). The study aims to determine in which biofluids and tissues researchers should measure alpha-synuclein to diagnose PD, track progression and evaluate the impact of therapies with the potential to slow or stop disease progression.

Gut Microbiota: A New Kind of Biomarker?

The composition of the gut microbiota provides a huge potential of new biomarkers for indicating intestinal conditions. Experts presented new findings at the Gut Microbiota for Health World Summit 2016 (March 5/6, Miami).

Biocept to Collaborate on Biopharma Company Clinical Trial by Identifying Biomarkers Found in Cerebral Spinal Fluid for Patients with Lung Cancer that has Spread to the Brain

Biocept, Inc. (NASDAQ: BIOC), a molecular diagnostics company commercializing and developing liquid biopsies to improve the detection and treatment of cancer, announces a collaboration on a biopharmaceutical company clinical trial analyzing biomarkers using both circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) from cerebrospinal fluid (CSF). The trial is being conducted in patients with non-small cell lung cancer (NSCLC) whose disease has spread to the brain or membranes surrounding the brain and spinal cord, known as leptomeningeal disease.

Cancer’s Hidden Protein – Protein Variants Could Be the Key to Early Cancer Diagnosis

Princeton based Biotech Support Group recently announced that it has submitted provisional patents disclosing its data on many common proteins dysregulated in cancer. This breakthrough research shows that most of these biomarkers are believed to be dysregulated regardless of the primary tumor, stage of progression or tumor burden.

QIAGEN Partners to Develop Novel Companion Diagnostic in Lung Cancer

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) recently announced a partnership with Mirati Therapeutics, Inc. (NASDAQ: MRTX) to co-develop and commercialize a companion diagnostic test to guide the use of Mirati’s glesatinib (MGCD265), a targeted therapy under development for non-small cell lung cancer (NSCLC). The companies aim to create a regulator-approved test to personalize treatment decisions in NSCLC by detecting RNA biomarkers produced by exon 14 skipping mutations of the MET gene.