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Archives for December 2015

Johns Hopkins Medicine to Share Best Practices in the Apervita Health Analytics & Data Marketplace

Apervita, Inc., creators of the first real-time, cloud-based platform and marketplace for using and sharing health analytics & data, today announced Johns Hopkins Medicine has joined the rapidly growing number of leaders in health care research distributing algorithms proven to transform care delivery through the Apervita Market. For the first time, health enterprises everywhere will be able to access and deploy the extensive library of Johns Hopkins health innovations to improve patient outcomes.

NUS Scientists a Step Closer to Developing Blood Test to Monitor Status of Cancer and Treatment Outcome

Scientists from the National University of Singapore (NUS) have developed a novel technique to efficiently culture clusters containing circulating tumour cells (CTCs) in 14 days that could be used to predict the outcome of cancer treatment as well as monitor the status of cancer. Using the technique, the team achieved a success rate of more than 60 per cent in culturing CTCs from patients with metastatic breast cancer, the highest known success record to-date. This breakthrough brings researchers a step closer towards enabling personalised cancer treatment and monitoring.

Clinical Trial Design Improvements Could Spur Drug Development for Autism and Traumatic Brain Injury, While Biomarkers Appear Key in the Discovery of Treatments for Amyotrophic Lateral Sclerosis

Decision Resources Group finds that neurologists specializing in autism spectrum disorder (ASD) consider its heterogeneity a key obstacle to developing pharmacotherapies that effectively address core behavioral symptoms—the greatest unmet need among patients with ASD. Relying on differences in clinical presentation to guide patient selection for clinical trials is put forward as a possible way to enhance the chance of observing a therapeutic effect, a suggestion that is echoed by neurologists treating traumatic brain injury (TBI) patients, a neurological condition with similarly complex pathophysiological underpinnings. For amyotrophic lateral sclerosis (ALS), a rare disease that in most cases is not caused by genetic mutations known to date, the development of biomarkers is a prerequisite to discovering effective disease-modifying interventions, according to interviewed experts.

Affymetrix and XRGenomics LTD to Collaborate on Development of a New Generation of Diagnostic Tests for Age-Related Diseases

Affymetrix, Inc. (NASDAQ: AFFX) and XRGenomics LTD, a UK based biotechnology company, announced today that they will collaborate on research and development of a new generation of diagnostic tests for age-related diseases. Over 50% of healthcare costs are spent on those aged 65 and older and according to the G8 Summit 2013, age-related diseases could bankrupt Western medicine by 2050. New solutions are required to deliver efficient and effective care.

Banyan Biomarkers Reports Successful Clinical Trial Results of Blood Test to Evaluate Mild and Moderate Traumatic Brain Injury

Banyan Biomarkers, Inc., the leader in developing biomarkers for traumatic brain injury (TBI), today announced the results of a clinical study utilizing a blood test to evaluate mild and moderate TBI. The results, published online in the Journal of Neurotrauma, indicate that the two highly brain specific biomarkers in Banyan Biomarkers’ blood test, ubiquitin c-terminal hydrolase-L 1 (UCH-L1) and glial fibrillary acidic protein (GFAP), are detectable in blood shortly after a TBI. The test was able to identify 100% of the trial subjects who went on to have a positive computed tomography (CT) scan of the head. The results demonstrate that early biomarker testing for patients with mild to moderate TBI has the potential to provide clinicians with objective evidence needed to reduce CT use that is associated with increased healthcare costs and developing cancer over the long term.