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Archives for January 2012

Evotec and Harvard University Expand Strategic Alliance into Kidney Disease

Evotec AG recently announced a second strategic alliance with Harvard University, this time including Brigham and Women’s Hospital aimed at discovering and developing new biomarkers and treatments in the field of kidney disease. The first successful collaboration ‘CureBeta’ was established in March 2011 to develop new diabetes therapies targeting beta cell regeneration.

Quintiles Forms New Biomarker Research and Development Company

Continuing its commitment to advancing personalized medicine by offering world-leading experts and cutting-edge tools, Quintiles today announced that it has invested in a new company formed to provide oncology consulting services and new cancer biomarkers, the key to scientific selection of the right drug for the right patient.

International Research Team Discovers Genes and Disease Mechanisms Behind a Common Form of Muscular Dystrophy

Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by a scientist at Fred Hutchinson Cancer Research Center has identified the genes and proteins that damage muscle cells, as well as the mechanisms that can cause the disease. The findings are online and will be reported in the Jan. 17 print edition of the journal Developmental Cell.

Study Finds a Diet Rich in Slowly Digested Carbs Reduces Markers of Inflammation in Overweight and Obese Adults

Among overweight and obese adults, a diet rich in slowly digested carbohydrates, such as whole grains, legumes and other high-fiber foods, significantly reduces markers of inflammation associated with chronic disease, according to a new study by Fred Hutchinson Cancer Research Center. Such a “low-glycemic-load” diet, which does not cause blood-glucose levels to spike, also increases a hormone that helps regulate the metabolism of fat and sugar. These findings are published online ahead of the February print issue of The Journal of Nutrition.

New Test Spots Early Signs of Inherited Metabolic Disorders

A team of scientists, led by researchers at the University of California, San Diego School of Medicine and Zacharon Pharmaceuticals, have developed a simple, reliable test for identifying biomarkers for mucopolysaccharidoses (MPS), a group of inherited metabolic disorders that are currently diagnosed in patients only after symptoms have become serious and the damage possibly irreversible. The findings will be published online January 8 in the journal Nature Chemical Biology.