Quantcast

Industry news that matters to you.  Learn more

Scientists Discover Why Some Cancers May Not Respond to Immunotherapy

UCLA scientists have discovered that people with cancers containing genetic mutations JAK1 or JAK2, which are known to prevent tumors from recognizing or receiving signals from T cells to stop growing, will have little or no benefit from the immunotherapy drug pembrolizumab. This early-stage research has allowed them to determine for the first time why some people with advanced melanoma or advanced colon cancer will not respond to pembrolizumab, an anti-PD-1 treatment.

Sentinels in the Blood: a New Diagnostic for Pancreatic Cancer

Despite enormous research strides, detection methods for many diseases remain cumbersome and expensive, and often uncover illness only at advanced stages, when patient outcomes can be bleak. One such illness is pancreatic cancer, which may display no obvious symptoms in its early stages, yet can develop aggressively. Indeed, according to the American Cancer Society, a staggering 80 percent of those stricken with this form of cancer die within 1 year of diagnosis.

GenomeDx Announces Research Collaboration with Astellas to Identify Genomic Drivers of Patient Response to XTANDI (enzalutamide) Capsules

GenomeDx Biosciences recently announced that it has entered into a research collaboration with Astellas, a leading global pharmaceutical company, to apply genomic tumor profiling using GenomeDx’s Decipher® Classifier and Decipher GRID® as a potential aid in the identification of prostate cancer patients undergoing active surveillance who may benefit from treatment with XTANDI® (enzalutamide).

Doctors Create ‘MAGIC Algorithm’ to Predict Bone Marrow Transplant Patients’ Risk of Dying

Researchers at Mount Sinai Health System have discovered a way to predict whether blood cancer patients who received a bone marrow transplant will develop graft-versus-host disease, a common and often lethal complication, according to a study published in JCI (The Journal of Clinical Investigation) Insight.

Bristol-Myers Squibb and GeneCentric Diagnostics Announce Exploratory Biomarker Research Collaboration

Bristol-Myers Squibb Company (NYSE:BMY) and GeneCentric Diagnostics, Inc. recently announced a biomarker research collaboration to explore whether the application of GeneCentric’s Cancer Subtype Platform (CSP™) might be able to identify translational biomarkers for Opdivo (nivolumab), which may help inform future clinical trials. Additionally, GeneCentric announced it has secured equity funding from Bristol-Myers Squibb that will support the clinical development of GeneCentric’s CSP™ and build-out of GeneCentric’s new laboratory in Research Triangle Park.