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Archives for June 2010

New Research Profiles the State of Biomarkers in Product Development

Industry Standard Research (ISR) today announced the release of The State of Biomarkers in Drug Development report. 44 pharmaceutical and biotechnology professionals provided their strategies, insights, and predictions in this snapshot of a rapidly evolving market. In total, 37 significant pharma and biotech companies contributed to this endeavor.

Vermillion Announces Issuance of Patent for Alzheimer’s Disease Diagnosis

Vermillion, Inc., a molecular diagnostics company, today announced that the United States Patent and Trademark Office (USPTO) has issued a notice of allowance of a patent entitled “Biomarkers for Alzheimer’s disease” to the Company. The patent claims are directed to biomarker combinations for the diagnosis and management of Alzheimer’s disease and to the measurement of the biomarkers by a variety of methods, including mass spectrometry and immunoassay.

TcLand Teams Up with Spanish Institute to Develop Assay for Predicting Response To TNFalpha Therapy

TcLand Expression is teaming up with the Hospital Vall d-Hebron Research Institute (HVIR) in Spain to develop a biomarker-based assay for predicting individual patients’ responses to TNFα blocker therapy for rheumatoid arthritis (RA). The collaboration agreement gives TcLand exclusive, worldwide rights to HVIR’s IP covering response-related biomarkers discovered by the Institute’s Sara Marsal, M.D., director of the Grup de Recerca de Reumatologia.

Aeterna Zentaris Announces Collaboration with Almac to Develop Therapy and Companion Diagnostic in Cancer

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced a collaborative study with Almac’s Diagnostics division for the Company’s doxorubicin luteinizing hormone-releasing hormone (LHRH) targeted conjugate compound, AEZS-108, aimed at determining LHRH receptor expression through the development of a companion diagnostic tool. Selection for treatment with AEZS-108 is determined on the basis of LHRH receptor expression, currently measured immunohistochemically. In humans, LHRH receptors are expressed in ovarian, endometrial, breast, bladder, prostate and pancreatic tumors. AEZS-108 is currently in Phase 2 trials for advanced LHRH receptor positive ovarian and endometrial cancer.

Phadia Chooses Aushon BioSystems’ Microarray Technology to Accelerate Diagnostic Allergen and Autoimmunity Assay Development

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, announced today that Phadia, the world leader in allergy blood testing diagnostics, will utilize the Aushon 2470 Arrayer technology in its Multiplexing Diagnostics GmbH division. The 2470 will enable Phadia to advance its research efforts focusing on the characterization of new allergens, and the discovery of patterns in molecular diagnosis for allergy and autoimmunity.